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本课程起止时间为:2022-08-22到2022-12-31

Introduction of Molecular cell biology Cell theory-test

1、 问题:What did Leeuwenhoek do?
选项：
A: Looked at cork
B:Stated that plants are made of cells
C: Stated that animals are made of cells
D:Used simple light microscope and saw microorganisms
答案: 【Used simple light microscope and saw microorganisms】

2、 问题:He discovered that all animals were made of cells, which contributed to the development of the cell theory:
选项：
A:A.van Leeuwenhoek
B: Robert Hooke
C: Zacharias Jansse
D:Theodor Schwann
答案: 【Theodor Schwann】

3、 问题:Who was the first person to see cells under the microscope and give them a name?
选项：
A:A.van Leeuwenhoek
B:Robert Hooke
C:Theodor Schwann
D:Zacharias Jansse
答案: 【Robert Hooke】

4、 问题:Which of the following is NOT one of the main components of the cell theory?
选项：
A:cells must contain DNA
B: all living things are made of cells
C:cells can only come from other cells
D:cells are the basic unit of life
答案: 【cells must contain DNA】

Culturing and visualizing cells Culturing and visualizing cells-test

1、 问题: The most direct source of monoclonal antibodies are __ cells.
选项：
A:B lymphocytes
B:T lymphocytes
C:myeloma
D:Hybridoma
答案: 【Hybridoma】

2、 问题:The fluorescent properties of dyes such as FITC can provide information on the
选项：
A:location of specific proteins.
B:concentration of  ions in specific regions of the cell.
C:the amount of  DNA in a cell.
D:volume of a cell.
答案: 【location of specific proteins.】

3、 问题:What factors necessary for growth of animal cells in culture are provided by serum?
选项：
A:amino acids
B:precursors of DNA synthesis
C:growth factors
D:vitamins
答案: 【growth factors 】

4、 问题:What is the advantage of using GFP-tag to visualize specific proteins, instead of staining cells with fluorescent dyes that bind to the target protein?
选项：
A:GFP fusions enable one to track changes in the location of the protein in living cells; staining usually requires fixed cells
B:GFP fusions enable higher resolution than staining with fluorescent probes.
C:GFP permits the position of the protein in the cell more precisely than fluorescent probes
D:GFP fusions are not subject to artifacts; fluorescent probes may introduce background artifacts.
答案: 【GFP fusions enable one to track changes in the location of the protein in living cells; staining usually requires fixed cells】

5、 问题:Which one cleaves pre-miRNA in the cytoplasm to produce miRNA?
选项：
A:Dicer
B:RISC
C:shRNA
D:siRNA
答案: 【Dicer】

6、 问题:A single monoclonal antibody can bind to several different sites on an antigen
选项：
A:正确
B:错误
答案: 【错误】

7、 问题:RNAi can be mediated just by introducing the already processed miRNA/siRNA into cells
选项：
A:正确
B:错误
答案: 【正确】

8、 问题:_______  degrades mRNAs with sequences complementary to a bound siRNA
答案: 【RISC】

Biomembrane Structure Biomembrane Structure-test

1、 问题:All the following statements describe biomembranes except:
选项：
A:Different biomembranes may contain different proportions of the same phospholipids.
B: The two leaflets of a biomembrane may contain different phospholipids.
C: Some biomembranes have free edges.
D:Some phospholipids and cholesterol may cluster to form lipid rafts.  
答案: 【 Some biomembranes have free edges.】

2、 问题: The major site of lipid synthesis in eukaryotic cells is the
选项：
A:Nucleus
B:Endoplasmic reticulum
C:Mitochondria
D:Cell membrane
答案: 【Endoplasmic reticulum】

3、 问题:Phospholipids with short or unsaturated fatty acyl chains
选项：
A:decrease membrane fluidity.
B:increase membrane fluidity.
C: cause biomembranes to become thicker
D:allow hydrophilic molecules to diffuse across the lipid bilayer.
答案: 【increase membrane fluidity.】

4、 问题: The _ are transmembrane proteins.
选项：
A:lipid-anchored membrane proteins
B:integral membrane proteins
C:peripheral membrane proteins
D:extracellular matrix proteins
答案: 【integral membrane proteins】

5、 问题:Glycolipids and glycoproteins are especially abundant in the
选项：
A: nucleus.
B:mitochondrial inner membrane
C:cytosol
D:plasma membrane
答案: 【plasma membrane】

6、 问题:Phosphate containing lipids include all of the following except 
选项：
A: phospholipids.
B:sphingolipid
C:triglyceride
D:phosphatidylinositol
答案: 【triglyceride】

7、 问题:A lipid bilayer is the fundamental structural component of all cell membranes.
选项：
A:正确
B:错误
答案: 【正确】

8、 问题:Maintenance of the lipid bilayer in the plasma membrane requires special enzymes and the hydrolysis of ATP.
选项：
A:正确
B:错误
答案: 【错误】

9、 问题:The most abundant lipids in cell membranes are ____.
答案: 【phospholipids】

10、 问题:Sugar-containing lipids called ______ are found only in the outer half of the bilayer and their sugar groups are exposed ac the cell surface.
答案: 【glycolipids】

Integrating cells into tissues Ch20 Test -single answer choice

1、 问题:The functions of the extracellular matrix includea. supporting differentiation.b. inducing morphogenesis.c. binding growth hormones.d. all of the above
选项：
A:a
B:b
C:c
D:d
答案: 【d】

2、 问题:Desmosomes:a. associate with actin filaments on the cytoplasmic side.b. contain the transmembrane proteins desmoglein and desmocollin.c. inhibit transfer of membrane proteins from the basolateral to the apical domain.d. contain integrins.
选项：
A:a
B:b
C:c
D:d
答案: 【b】

3、 问题:The major families of cell surface adhesion molecules includea. cadherins and selectins.b. integrins.c. the Ig-superfamily.d. all of the above
选项：
A:a
B:b
C:c
D:d
答案: 【d】

4、 问题: Vertebrate gap junctions are composed ofa. adherins.b. collagens.c. connexins.d. integrins.

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