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第三章 糖代谢 单元测验3

1、 问题:The enzyme required for the reverse reaction catalyzed by hexokinase is
选项:
A:fructose-1,6-bisphosphatase
B:glucose- 6-phosphatase
C:phosphofructokinase-1
D:phosphohexose isomerase
E:pyruvate kinase
答案: 【glucose- 6-phosphatase

2、 问题:Under anaerobic condition, the metabolic fate of NADH + H+ generated in glycolysis pathway is
选项:
A:Reduce 3-phosphoglycerate to 3-phosphoglyceraldehyde
B:To be oxidized via respiratory chain to supply energy
C:Reduce pyruvate to lactate
D:Used to break down fructose-1, 6-bisphosphate
E:Used for biosynthesis of fatty acids
答案: 【Reduce pyruvate to lactate

3、 问题:The end product of aerobic oxidation of glucose is
选项:
A:CO2+H2O+ATP
B:lactate
C:pyruvate
D:acetyl CoA
E:citrate
答案: 【CO2+H2O+ATP

4、 问题:The biochemical mechanism of hemolytic anemia caused by deficiency of glucose-6-phosphate dehydrogenase is
选项:
A:Inhibition of pentose phosphate pathway results in deficiency of phosphopentose.
B:Deficiency of NADPH+H+ results in low level of GSH in RBC.
C:Metabolic disorder of glycolysis pathway results in energy deficiency.
D:Disorder of hemoglobin synthesis
E:None of the above
答案: 【Deficiency of NADPH+H+ results in low level of GSH in RBC.

5、 问题:Under resting state, most of the blood glucose can be used by the following tissue/organ
选项:
A:liver
B:brain
C:kidney
D:fat
E:muscle
答案: 【brain

6、 问题:The energy in mature red blood cells come from
选项:
A:aerobic oxidation of glucose
B:glycogen degradation
C:pentose phosphate pathway
D:glycolysis
E:gluconeogenesis
答案: 【glycolysis

7、 问题:The false statement about the citric acid cycle is
选项:
A:Decarboxylation occurs twice per cycle.
B:One molecule of acetyl CoA is oxidized in each cycle.
C:The complete oxidation of one molecule of acetyl CoA produces 10 molecules of ATP.
D:4 NADH+H+are produced per cycle.
E:Acetyl CoA is first condensed with oxaloacetate to form citrate.
答案: 【4 NADH+H+are produced per cycle.

8、 问题:The product(s) of acetyl CoA oxidized by citric acid cycle is/are
选项:
A:citric acid
B:oxaloacetic acid
C:CO2 and H2O
D:oxaloacetic acid and CO2
E:CO2 and 4 reduction equivalents
答案: 【CO2 and 4 reduction equivalents

9、 问题:The deficient enzyme in patients with hemolytic jaundice caused by eating fresh broad beans is
选项:
A:3-phosphoglyceraldehyde dehydrogenase
B:isocitrate dehydrogenase
C:succinate dehydrogenase
D:glucose-6-phosphate dehydrogenase
E:gluconate-6-phosphate dehydrogenase
答案: 【glucose-6-phosphate dehydrogenase

10、 问题:Which of the following description about glycogen phosphorylase is false
选项:
A:It is the key enzyme for glycogen decomposition.
B:There are two forms including phosphorylase a and phosphorylase b.
C:Phosphorylase a is inactive form.
D:Enzyme activity is regulated by hormones.
E:Phosphorylase b is activated by phosphorylase kinase.
答案: 【Phosphorylase a is inactive form.

11、 问题:The end product of anaerobic glycolysis in human cells is
选项:
A:acetone 丙酮
B:lactic acid 乳酸
C:propionic acid 丙酸
D:pyruvic acid 丙酮酸
E:ethanol 乙醇
答案: 【lactic acid 乳酸

12、 问题:The most important key enzyme that regulates the glycolysis is
选项:
A:Glucose kinase
B:Phosphofructokinase-1
C:Pyruvate kinase
D:Phosphoglycerate kinase
E:Fructose-1,6-bisphosphatase
答案: 【Phosphofructokinase-1

13、 问题:The reason why muscle glycogen breakdown cannot directly replenish blood glucose is
选项:
A:lack of glucose-6-phosphatase
B:lack of phosphorylase
C:lack of debranching enzyme
D:lack of hexokinase
E:low contents of muscle glycogen
答案: 【lack of glucose-6-phosphatase

14、 问题:The hormone that inhibit gluconeogenesis is
选项:
A:growth hormone
B:insulin
C:epinephrine 肾上腺素
D:glucagon
E:glucocorticoid 糖皮质激素
答案: 【insulin

15、 问题:The high energy compound directly generated by substrate level phosphorylation in the tricarboxylic acid cycle is
选项:
A:ATP
B:CTP
C:GTP
D:TTP
E:UTP
答案: 【GTP

16、 问题:The citric acid cycle occurs in
选项:
A:Mitochondria
B:Nucleus
C:Endoplasmic reticulum (内质网)
D:Cytoplasm
E:Golgi body
答案: 【Mitochondria

17、 问题:Cofactors of the pyruvate dehydrogenase complex include
选项:
A:NAD+
B:CoASH
C:TPP
D:FAD
E:FMN
答案: 【NAD+;
CoASH;
TPP;
FAD

18、 问题:The correct descriptions about glycogen synthase are
选项:
A:It is the key enzyme for glycogen synthesis.
B:There are two forms: phosphorylation and dephosphorylation.
C:The phosphorylation form is inactive.
D:Glycogen synthase is activated by protein kinase A.
E:Enzyme activity is regulated by hormones.
答案: 【It is the key enzyme for glycogen synthesis.;
There are two forms: phosphorylation and dephosphorylation.;
The phosphorylation form is inactive.;
Enzyme activity is regulated by hormones.

19、 问题:The raw materials for gluconeogenesis include
选项:
A:pyruvate
B:some amino acids
C:lactate
D:glycerol
E:acetyl CoA
答案: 【pyruvate;
some amino acids;
lactate;
glycerol

20、 问题:During starvation, which of the following pathways have increased enzyme activity in liver
选项:

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